Effectiveness Of CBD Against Covid And It’s Implications

EFFECTIVENESS OF CBD AGAINST COVID AND ITS IMPLICATIONS

Lately a lot of studies are coming on the main front regarding the greatest medical pandemic in the world known as COVID-19. Different organizations are coming up with different solutions to deal with this situation of extreme disturbance. Amidst all this, researchers and medical analysts have also come up with a new but surprising discovery of a marijuana based compound for the treatment of COVID. This compound of marijuana is known as cannabidiol and according to researchers,it functions by blocking the SARS COV 2 virus from entering the living cell of organisms. Marsha Rosner says, “We do not know yet if CBD can prevent COVID but we think our results provide a strong base for conducting a clinical trial”.

I went through a couple of articles during my research about this compound and it is important to mention here that it was not as simple enough to just recognize cannabidiol as an antiviral compound against COVID. The chase towards a formidable conclusion was in the form of steps and with each step new revelations, evidences and facts came up. At first the researchers who initially came up with this and did significant studies and testing regarding this compound included Marsha Rosner, Robin Duncan and their accomplices. Research groups of some universities are also worthy of some credit.

While talking about the effectiveness of this compound, it would be meaningless to state it without its actual functioning. What CBD actually does is that it enhances the host stress response system of an organism against different invaders. This host stress response system basically senses any threat by some invading molecules, therefore motivates the production of protective chemicals. Research groups also performed a series of testing to draw these answers. Their testing started initially from experimentations upon isolated living cells in laboratories and eventually getting the promotion of extending it to whole organisms like mice to even humans.

I would like share a test result, which the researchers drew in order to explain the validity of CBD as an effective compound.Following were the results; lung cells of mice infected with COVID in presence of low dosage of CBD showed overall 4.8 times low viral load in lungs and 3.7 times lower in Nasal cavities in comparison to CBD free mice. Regarding it Marsha Rosner says, “We show that CBD can stop replication of SARS COV 2 in cells in a dish and that it acts up to 15 hours after infection so it suggests it might be effective even at early times after virus enters cell”.

There is also a misconception in the minds of a vast majority of people, that marijuana and CBD are totally the same thing and that smoking marijuana would come out to be advantageous to them. Well that is totally wrong. Actually it must be kept in mind that the plant marijuana consists of a number of constituent compounds. Out of which we have this one named CBD for ourselves as a source of antiviral drugs against COVID. Here it is to be noted that not all CBD products can serve the holy purpose of treating COVID. Only the one, approved by FDA, is suitable for treating COVID. The purity proportion of the compound also matters a lot and it should be kept in mind that the CBD approved for treating seizures and epilepsy and other related diseases have a purity composition of about 98 percent. So any low credibility CBD, commercially available for common use would not cause any significant effect.

After vigorous testing it also came to notice that there are some other compounds derived from marijuana origin too such as the cannibirgerloic (CBGA) and canna Bidiolic acid (HBDCA). These compounds may help in some way to some extent but in the long term CBD is for use. Here it is also to be kept in mind of the athletes that CBD is a compound most active in conditions when it is used isolated from the other compounds because the other compounds tend to lower it reactivity. So instead of smoking marijuana that may further damage the health of the lungs or a human body it’s better to use CBD based products for betterment. Marsha Rosner said,” smoking or vaping won’t protect you against COVID”.

When researchers studied the effect of psychoactive compounds, that make a person high, activity with regards to COVID they came to the conclusion that they do not stop COVID viruses from entering the cells. Also it was formulated by the researchers that the right amount of dosage is equally as important as any other thing. Potentially it’s better to have low dosage of the CBD compound in order to experience the effectiveness because when it filters through livers there are this way less chances of side effects according to the researcher Marsha Rosner.

Researchers, during the process of testing also faced a number of challenges. Initially they required funding, so they contacted different government and private funding organizations as they required big sample space. Plus, to experiment its authenticity in real terms they had to gather some people as volunteers which wasn’t as easy a job because people tend to hesitate with some new experiments. Secondly during the omicron variant they got further limited as the current variant was only given by mild symptoms and in those symptoms it is not possible to test the volunteers.

At the end I would like to mention something to all the readers which is of great importance. It is the fact that this method of treatment towards COVID is although proving to be very beneficial day by day however, it has not been completely approved yet. In other words, the use of masks and vaccinations as prescribed by the government is still considered as the most effective way of preventing COVID and therefore, their use must not be discontinued in any way. Marsha Rosner herself says in this regard, “Vaccine induced antibodies and antibody drugs are much more effective in blocking infection”.

Effectiveness of CBD against COVID and its Implications

Lately, a lot of studies are coming on the main front regarding the greatest medical pandemic in the world, known as COVID-19. Different organizations are coming up with other solutions to deal with this situation of extreme disturbance. Amidst this, researchers and medical analysts have also come up with a new and surprising discovery of a marijuana-based compound for the treatment of COVID. This compound of marijuana is known as cannabidiol, and according to researchers, it functions by blocking the SARS COV 2 virus from entering the living cell of organisms. Marsha Rosner says, "We do not know yet if CBD can prevent COVID, but we think our results provide a strong base for conducting a clinical trial." 

I went through a couple of articles during my research about this compound, and it is essential to mention here that it was not as simple enough just to recognize cannabidiol as an antiviral compound against COVID. The chase towards a formidable conclusion was in the form of steps, and with each step, new revelations, evidence, and facts came up. At first, the researchers who initially came up with this and did significant studies and testing regarding this compound included Marsha Rosner, Robin Duncan, and their accomplices. Research groups of some universities are also worthy of some credit. 

While talking about the effectiveness of this compound, it would be meaningless to state it without its actual functioning. What CBD actually does is that it enhances an organism's host stress response system against different invaders. This host stress response system basically senses any threat by some invading molecules, therefore, motivates the production of protective chemicals. Research groups also performed a series of testing to draw these answers. Their testing started initially from experimentations upon isolated living cells in laboratories and eventually getting the promotion of extending it to whole organisms like mice to even humans. 

I would like to share a test result that the researchers drew in order to explain the validity of CBD as an effective compound. Following were the results; lung cells of mice infected with COVID in the presence of a low dosage of CBD showed overall 4.8 times low viral load in lungs and 3.7 times lower in Nasal cavities in comparison to CBD-free mice. Regarding it, Marsha Rosner says, "We show that CBD can stop the replication of SARS COV 2 in cells in a dish and that it acts up to 15 hours after infection, so it suggests it might be effective even at early times after the virus enters cell".

There is also a misconception in the minds of a vast majority of people that marijuana and CBD are totally the same things and that smoking marijuana would come out to be advantageous to them. Well, that is totally wrong. Actually, it must be kept in mind that the plant marijuana consists of a number of constituent compounds. Out of which, we have this one named CBD for ourselves as a source of antiviral drugs against COVID. Here it is to be noted that not all CBD products can serve the holy purpose of treating COVID. Only the one approved by FDA is suitable for treating COVID. The purity proportion of the compound also matters a lot, and it should be kept in mind that the CBD approved for treating seizures and epilepsy and other related diseases have a purity composition of about 98 percent. So any low credibility CBD commercially available for everyday use would not cause any significant effect. 

After vigorous testing, it also came to notice that some other compounds derived from marijuana origin, such as the cannibirgerloic (CBGA) and canna Bidiolic acid (HBDCA). These compounds may help in some way to some extent, but in the long term, CBD is for use. Here it is also to be kept in mind of the athletes that CBD is most active in conditions when used isolated from the other compounds because the other compounds tend to lower their reactivity. So instead of smoking marijuana that may further damage the health of the lungs or the human body, it's better to use CBD-based products for betterment. Marsha Rosner said," smoking or vaping won't protect you against COVID." 

When researchers studied the effect of psychoactive compounds that make a person high activity with regards to COVID, they came to the conclusion that they do not stop COVID viruses from entering the cells. Also, it was formulated by the researchers that the right amount of dosage is equally as significant as any other thing. Potentially it's better to have a low dosage of the CBD compound in order to experience the effectiveness because when it filters through livers, there are this way fewer chances of side effects, according to the researcher Marsha Rosner. 

Researchers, during the process of testing, also faced a number of challenges. Initially, they required funding, so they contacted the different government and private funding organizations as they needed ample sample space. Plus, to experiment with its authenticity in real terms, they had to gather some people as volunteers, which wasn't as easy a job because people tend to hesitate with some new experiments. Secondly, during the omicron variant, they got further limited as the current variant was only given mild symptoms, and in those symptoms, it is not possible to test the volunteers. 

In the end, I would like to mention something to all the readers which are of great importance. It is a fact that this method of treatment towards COVID is, although proving to be very beneficial day by day; however, it has not been wholly approved yet. In other words, the use of masks and vaccinations as prescribed by the government is still considered the most effective way of preventing COVID, and therefore, their use must not be discontinued in any way. Marsha Rosner herself says in this regard, "Vaccine-induced antibodies and antibody drugs are much more effective in blocking infection."

REFERENCES:

1-     Stephanie.p . (2022) . Can CBD really prevent COVID-19 infection? Scientists hope to find out . https://www.livescience.com/cbd-cannabidiol-may-block-covid-infection 

2-     Nancy.L . (2022) . Cannabis compound CBD stops coronavirus in test tube, but can it treat COVID?. https://www.reuters.com/business/healthcare-pharmaceuticals/cannabis-compound-cbd-stops-coronavirus-test-tube-can-it-treat-covid-2022-01-25/

3-     Media relations. (2022) . CBD might help prime cells against COVID. https://uwaterloo.ca/news/media/cbd-might-help-prime-cells-against-covid